Hilton Jacksonville at Mayo Clinic is a newly built, non-smoking hotel set on the Mayo Clinic Jacksonville campus, designed for straightforward access to appointments and conferences while still keeping the coast within easy reach. A daily shuttle links the medical facilities, and the hotel supports accessibility needs with ADA guestrooms plus access to wheelchairs and certain medical equipment. Rooms and suites follow a modern Hilton template with practical comforts such as streaming entertainment, and select options add water views. Coastal Kitchen, the on-site restaurant, serves a breakfast buffet and made-to-order omelets, then shifts to steaks, seafood, salads, and artisanal pizzas, backed by a solid wine list and cocktails; room service runs to 10 pm. Amenities include free parking, free Wi‑Fi, EV charging, a heated outdoor pool, a fitness center, and 16,500 sq ft of event space. Jacksonville Beaches and St. Johns Town Center are both within about eight miles.